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ea0099ep638 | Calcium and Bone | ECE2024

Evaluation of Irisin levels in a group of young patients with Cerebral Palsy compared with healthy matched controls

Saponaro Federica , Sgandurra Giuseppina , Beani Elena , Paolicelli Paola , Brunori Elena , Tinelli Francesca , Filogna Silvia , Cioni Giovanni , Chiellini Grazia , Polini Beatrice , Ricardi Caterina , Pignataro Patrizia , Colucci Silvia , Dicarlo Manuela , Zerlotin Roberta , Colaianni Graziana , Comberiati Pasquale , Baroncelli Gianpiero , Gamborino Agnese , Saba Alessandro , Grano Maria

Introduction: Cerebral palsy (CP) is the most common chronic disability in childhood, burden by motor, sensation, cognition, feeding and communication impairment. A serious concern in children with CP is bone/muscle health deterioration, which negatively impacts the already reduced quality of life (QoL). Irisin is a myokine secreted by contracting muscle, which mediates beneficial effects on several targets, including brain. The aim of this pilot study was to evaluate serum le...

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Evaluation of Irisin levels in a group of young patients with Cerebral Palsy compared with healthy matched controls

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